MIRIADE is looking for a total of 15 Early Stage Researchers (ESRs) will be hosted across the network. The project will leverage existing proteomics datasets to identify the most promising candidate biomarkers for the major forms of dementias:
- ESR1 will develop an openly accessible integrated data platform for biomarker development.
- ESR project 2 will focus on the prediction of protein-antibody interactions success in biomarker assay development.
- ESR3 will characterise protein surface accessiblility states in specific biological matrices, to improve biomarker assay development.
- ESR4-6 will develop specific reaction monitoring assays and validate these in CSF and blood of patients with Alzheimer's disease (ESR4), frontotemporal dementia (ESR5) or dementia with Lewy Bodies (ESR6).
- ESR7-10 will develop novel immunoassays in CSF and blood for all dementias (ESR7); Alzheimer's disease (ESR8), frontotemporal dementia (ESR9) or dementia with Lewy Bodies (ESR10).
- ESR11 and 12 will focus on the market-ready development of plasma Abeta42 and Abeta40 assays (ESR11) or Neurofilament light (ESR12).
- ESR13 will develop reference methods for selected reaction monitoring (SRM) assays for Amyloid and Neurofilament light in cerebrospinal fluid and blood.
- ESR14 and 15 will focus on innovation of the process, in order to generate a roadmap for efficient biomarker development. ESR14 will study how data are organised, shared, reused and integrated in academia and ESR15 will compare and evaluate different workflows of biomarker development.
Next to your local PhD training, you will participate in an attractive educational programme customised to the MIRIADE early stage researchers. The MIRIADE training programme consists of annual training weeks across Europe to optimally develop your academic and transferable skills, as well as the basis of innovation and entrepreneurship. This training programme prepares you for a prosperous career as biomarker expert.
To be eligible for an early stage researcher position, the applicant must satisfy the following requirements conform the Marie Curie admission requirements:
- Must not already hold a PhD;
- Must be within the first four years (full-time equivalent) of their research career;
- Must not have resided or carried out their main activity (work, studies, etc.) within the host country for more than 12 months in the three years immediately prior to their recruitment.
Successful candidates will receive an attractive base-salary in accordance with the Marie Skłodowska-Curie Actions, for 36 months. The exact (net) salary depends on the EU-defined country correction factor, and on local tax regulations (for additional information see EU MSCA website). Fellows will also benefit from a mobility allowance. In addition, a family (if applicable) allowance (an additional financial allowance paid with the salary) is on offer to fellows with a spouse &/or child/children at time of recruitment.